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. 2022 Apr 11;13:866352. doi: 10.3389/fneur.2022.866352

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Copyright © 2022 Kajimoto, Kameda, Kambara, Kuroda, Tsuji, Nikaido, Saura and Wanibuchi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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MMSE (A) and FAB (B) for each patient over 4 years. (A) The MMSE remained almost unchanged for 4 years in many patients. MMSE showed a significant decrease in cases of dementia with Lewy bodies (DLB) and functional underdrainage associated with weight gain, which we named weight and abdominal pressure induced shunt trouble (WAIST). (B) FAB was also maintained at a high score for 4 years in many patients, but declined significantly in one patient who developed DLB, in two patients with no hobbies and a persistent inactive lifestyle, and in one patient with an underdrainage type of WAIST. MMSE, Mini-Mental State Examination; FAB, Frontal Assessment Battery; WAIST, weight and abdominal pressure induced shunt trouble.