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AUC0–24/MIC and Cmax/MIC ratios for both vancomycin and oritavancin
| Antibiotic | Ratio (mean ± SD) for R919 and R921
|
|
|---|---|---|
| AUC0–24/MIC | Cmax/MIC | |
| Oritavancina | 36,505.8 ± 5902.4 | 7,188.5 ± 675.5 |
| Oritavancin + albumin | 18,252.9 ± 2951.2 | 3,594.3 ± 337.7 |
| Vancomycin | 944.5 ± 81 | 73.7 ± 3.1 |
Both ratios are based on a MIC of 0.015 μg/ml.
