Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Feb 24;9(12):2105672. doi: 10.1002/advs.202105672

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 The Authors. Advanced Science published by Wiley‐VCH GmbH

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

The correlation between HTR1A expression and survival. a,b) High methylation levels of CpG site cg04694812, cg04427003, and cg04799838 in HTR1A were significantly correlated with shorter OS of breast cancer patients c) The expression of HTR1A was significantly upregulated after decitabine treatment. d,e) HTR1A CpG site in breast cancer tissues showed significantly higher methylation levels. f–h) The antitumor effect of ZdCyd and vilazodone in mouse xenograft models of MDA‐MB‐231 LM2. i,j) The correlation between HTR1A expression and survival was analyzed by the Cox proportional hazard regression model. k) Model of the mechanism of HTR1A in triple‐negative breast cancer. *p < 0.05 and **p < 0.01.