Table 4.

Performance of prediction models for LN metastasis

Dataset	AUC(95%CI)	Cutoff value	Sen	Spe	PPV	NPV	p Value
For TCGA cohort
Genetic model	0.70 (0.65–0.75)	0.41	0.87	0.48	0.62	0.79	3.23 × 10−13
Pathological model	0.73 (0.69–0.78)	0.47	0.75	0.59	0.64	0.71	1.99 × 10−17
Combined model	0.77 (0.73–0.81)	0.49	0.76	0.67	0.69	0.74	9.81 × 10−23
For validation cohort
Genetic model	0.75 (0.63–0.87)	0.58	0.83	0.65	0.76	0.74	3.33 × 10−4
Pathological model	0.73 (0.61–0.84)	0.53	0.51	0.84	0.81	0.57	1.10 × 10−3
Combined model	0.88 (0.79–0.96)	0.49	0.83	0.84	0.87	0.79	5.45 × 10−8

LN, lymph node.