Figure 2.

The ATG-dependent EVP secretome from BafA1 treated cells overlaps with previous proteomic analyses of the autophagy pathway. Venn diagrams showing: (A) The overlap of ATG-dependent EVP secretion candidates from BafA1 treated cells with the class I and class II BirA*-LC3B labeled secretome in Leidal et al. (2020). (B) The overlap of ATG-dependent EVP secretion candidates from BafA1 treated cells with the ATG7 and ATG12-dependent EV secretome in Leidal et al. (2020). (C) The overlap of ATG-dependent EVP secretion candidates from BafA1 treated cells with the ATG5-dependent bone-marrow–derived macrophage secretome in Kimura et al. (2017). (D) The overlap of ATG-dependent EVP secretion candidates from BafA1 treated cells with the autophagy interaction network defined in Behrends et al. (2010). (E) The overlap of ATG-dependent EVP secretion candidates from BafA1 treated cells with the autophagosome enriched proteome in Mancias et al. (2014). Core autophagy machinery and autophagy cargo receptors are highlighted in red.