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. 2022 Apr 11;16:858404. doi: 10.3389/fnins.2022.858404

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Copyright © 2022 Johnson, Dar, Donohue, Xu, Santiago, Selioutski, Marinescu, Maddox, Wu, Schifitto, Gosev, Choe and Khan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Glasgow Coma Scale Motor score (black), ASYM_rBF (red), and |ΔrBF_MAP| vs. MAP from the day of maximum ASYMrBF for subject 1 (A,C,E) and subject 11 (B,D,F) during their monitoring periods. (A) Subject 1, defined as non-comatose, displayed a constant GCS-Motor score of 6 while (B) subject 11, defined as comatose, varied between 1 and 4. ASYM_rBF data is shown for (C) subject 1 and (D) subject 11. The shaded region marked by the asterisk (*) denotes the maximum ASYM_rBF value that was chosen for each subject. | ΔrBF_MAP| of the gray shaded region shown in (C,D) is shown for (E) subject 1 and (F) subject 11. BFI data for day 3 of subject 11 was discarded due to low SNR thus ASYM_rBF was not calculated.