Table 1.
List of proteins identified in the DAF-15:mCherry IP by LC/MS/MS, ranked by peptide count, and listed with closest mammalian homolog by sequence similarity
| Protein | Peptide count range | Mammalian Homolog |
|---|---|---|
| DAF-15 | 22–75 | Raptor |
| LET-363 | 4–19 | Tor |
| MLST-8 | 3–10 | mLST8, mTor-associated protein |
| USP-5 | 2–3 | Ubiquitin carboxyl-terminal hydrolase 5 (USP5) |
| PGES-2 | 2–3 | Prostaglandin E synthase 2 (PTGES2) |
| MCM-7 | 1–3 | DNA replication licensing factor (MCM7) |
| B0513.5 | 2 | Proline dehydrogenase 1 (PRODH) |
| F38A1.8 | 2 | Signal recognition particle receptor subunit alpha (SRPRA) |
| HMG-11 | 2 | Uncharacterized |
| CCT-6 | 2 | T-complex protein 1 subunit zeta-2 isoform 3 (CCT6B) |
| F37C4.5 | 2 | None |
| CCT-1 | 2 | T-complex protein 1 subunit alpha (TCP1) |
| CHIN-1 | 2 | Beta-chimaerin (CHN2) |
| RHO-1 | 2 | Transforming protein RhoA |
| DHS-6/DHS-18 | 2 | Hydroxsteroid dehydrogenase-like protein 2 (HSDL2) |