Methods |
Parallel, study duration three months, follow up at three months |
Participants |
7272 participants, 50 per cent men, mean age 61 years, primary care, France |
Interventions |
SIMPLIFICATION OF DOSING REGIMENS: nicardipine 20 mg thrice daily versus nicardipine SR 50 mg twice daily |
Outcomes |
SELF REPORT: 82 per cent of participants in intervention group reported excellent adherence compared to 76 per cent among controls (p less than 0.001). Net reduction in blood pressure 0.2 mmHg (systolic) and 0.3 mmHg (diastolic). Not statistically significant, no exact p‐value reported. |
Notes |
No differential loss to follow‐up reported, high participant number due to large number of participating general practitioners, bias likely |