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. 2004 Jul 19;2004(3):CD004804. doi: 10.1002/14651858.CD004804

McKenney 1992.

Methods Two‐phase parallel, study duration two times 12 weeks, follow‐up at 12 and 24 weeks
Participants 70 participants, 70 per cent white, 59 per cent women, mean age 73 years
Interventions PATIENT MOTIVATION, SUPPORT AND REMINDERS: electronic medication aid cap with recording card and blood pressure cuff versus usual drug bottle
Outcomes PILL COUNT: 
 PHASE I: 
 Mean adherence 95 per cent in the intervention group compared to 78 per cent among controls (p equals 0.0002). Net reduction in blood pressure intervention versus control 4.8 mmHg systolic (p equals 0.0006) and 8.6 mmHg diastolic (p less than 0.001) 
 PHASE II: 
 Mean adherence rates 93.6 per cent for cap only (p equals 0.003), 98.7 per cent for cap and card (p less than 0.001), 100.2 per cent for cap card and cuff (p less than 0.001) versus 79 per cent in the control group. Net blood pressure reduction 12.3 mmHg systolic (p less than 0.01) and 19.2 mmHg diastolic (p equals 0.0001) for cap and card. Net blood pressure reduction 19.5mmHg systolic (p equals 0.0006) and 12.7 mmHg diastolic (p=0.0006) for cap, card and cuff.
Notes Nine patients required change of medication during second phase, and their blood pressure measurements were not included in the analysis.