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. 2022 Mar 25;8(2):25. doi: 10.3390/ijns8020025

Table 4.

Components of Pillar 2, Screening.

Parameter Description Score Interaction
Availability DBS test is available and in use 2 OR
DBS test is not yet available, but is in development with published evidence 1
Performance DBS test has a low false-positive rate and/or a high positive predictive value (PPV) 1 OR
DBS test has a high false-positive rate and/or a low PPV and/or requires additional confirmatory strategies that are available to improve screening performance 0.5