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. Author manuscript; available in PMC: 2022 Apr 25.
Published in final edited form as: Clin Cancer Res. 2008 Dec 15;14(24):8244–8252. doi: 10.1158/1078-0432.CCR-08-0939

Table 1.

Discovery phase cohort tumor characteristics

n (%)

Invasive tumor size (mm), n = 46
 <5 5 (10.9)
 5–10 5 (10.9)
 10–20 16 (34.8)
 20–50 17 (37.0)
 >50 3 (6.5)
Lymph node status (no. positive nodes), n = 45*
 0 13 (28.9)
 1–3 23 (51.1)
 4–9 6 (13.3)
 >10 3 (6.7)
Histologic subtype, n = 46
 Ductal NOS 41 (89.1)
 Lobular, pleomorphic 1 (2.2)
 Cribriform 1 (2.2)
 Mixed 2 (4.3)
 Too small to type 1 (2.2)
Grade, n = 43
 1 14 (32.6)
 2 19 (44.2)
 3 10 (23.3)
Lymphovascular invasion, n = 46
 Absent 10 (21.7)
 Present 36 (78.3)
% Overall tumor comprised by in situ carcinoma, n = 46
 <25 17 (37.0)
 25–50 15 (32.6)
 50–75 4 (8.7)
 >75 10 (21.7)
Uniform/mixed DCIS morphology, n = 45§
 Uniform 32 (69.6)
 Mixed 14 (30.4)

Abbreviation: NOS, not otherwise specified.

*

For 1 case, lymph node status not available.

Mixed subtypes included a mixture of NOS/tubular/cribriform and NOS/mucinous.

Three cases were too small to be graded.

§

Excludes one sample from a tumor with lobular carcinoma in situ only.