TABLE 2.
Frequency of IRF8 and IRF4 Expression in B-cell Malignancies
| Lymphoma Type | n | IRF8 |
IRF4 |
Coexpression |
|||
|---|---|---|---|---|---|---|---|
| n | % | n | % | n | % | ||
| Lymphoblastic | 5 | 5 | 100 | 0 | 0 | ||
| Burkitt | 8 | 8 | 100 | 0 | 0 | ||
| Follicular | 46 | 46 | 100 | 0 | 0 | ||
| Small lymphocytic | |||||||
| Small cells | 30 | 29 | 97 | 1 | 3 | 0 | |
| Proliferation centers | (19/30) | 19 | 100 | 19 | 100 | 19 | 100 |
| Mantle cell | 28 | 27 | 96 | 3 | 11 | 3 | 11 |
| Diffuse large B-cell | |||||||
| GCB | 39 | 39 | 100 | 5 | 13 | 5 | 13 |
| Non-GCB | 13 | 7 | 54 | 6 | 46 | 6 | 46 |
| Other | 6 | 6 | 100 | 0 | 0 | ||
| Marginal zone | 21 | 20 | 95 | 6 | 29 | 6 | 29 |
| Lymphoplasmacytic | 8 | 1 | 13 | 3 | 43 | 0 | |
| Plasmablastic | 14 | 0 | 9 | 100 | 0 | ||
| Multiple myeloma | 14 | 0 | 14 | 100 | 0 | ||
| Total | 232 | 188 | — | 47 | — | 20* | — |
*
Excluding proliferation centers of small lymphocytic lymphoma.