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. 2022 Apr 11;13:854445. doi: 10.3389/fimmu.2022.854445

Figure 1.

Figure 1

Magnetic resonance images of the patients. (A–F) Brain MRI of patient 1 was not remarkable with mild whiter matter abnormalities (indicated by arrows). (G–L) The MRI of cerebellum was not remarkable. (M–O) Brain MRI of patient 2 showed multiple abnormal signals in white matter in the bilateral cerebral hemisphere and brainstem (indicated by arrows). (P–R) The spine MRI of patient 2 showed long-segment spinal cord lesions from medulla to the C6 segment (indicated by arrows). After 3 months of treatment, (S–U) the brain MRI of patient 2 showed that the abnormal signals in the white matter and brainstem were reduced compared with those in (M–O). (V–X) The cervical MRI showed that the original abnormal signals in the spinal cord had disappeared. T1-weighted images: (A), (G), (J), (P), (V); T2-weighted images: (D), (H), (K), (Q), (R), (W); T2 fluid-attenuated inversion recovery sequence: (B), (E), (I), (L), (M), (N), (S), (T); T1-weighted images with contrast: (O), (U), (X); diffusion-weighted imaging sequence: (C), (F).