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. 2022 Apr 11;12:814413. doi: 10.3389/fcimb.2022.814413

Table 3.

Diagnostic performance of nested PCR and ELISPOT assay of 300 leprosy cases by diagnostic category.

All patients (n = 300) Nested PCR positive ELISPOT positive Nested PCR positive/ELISPOT negative ELISPOT positive/nested PCR negative
MB 194/202 (94%) 115/202 (56.9%) 79 (37.6%) 0
1–5 skin lesions 48/50 (92.4%) 46/50 (92%) 4 (8%) 2 (4%)
PB Pure neuritic leprosy 43/48 (89.6%) 44/48 (91.7%) 2 (4.2%) 1 (2.1%)
Not leprosy 0/10 (0%)
Household contact 5/150 (3.3%)
Health donor 5/150 (3.3%)