TABLE 3.
Effects of different concentrations of phosphate donors on the activity of dGK with various acceptors
3H-labeled substrate (10 μM) | Activity (nmol/min/mg)a with:
|
||
---|---|---|---|
5 mM ATP | 0.05 mM UTP | 5 mM ATP + 0.05 mM UTP | |
dGuo | 55 ± 2 | 77 ± 8 | 88 ± 2 |
dAdo | 7 ± 0.2 | 12 ± 2 | 11 ± 1 |
Ganciclovir | 0.5 ± 0.2 | 1.1 ± 0.3 | 1 ± 0.2 |
Values are means and standard deviations from three independent determinations.