The cyanidation of aromatic aldehydes with different proportions of water.
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Compound | HCOOH/H2O (%) | Time (h) | Yielda (%) |
1b | 60 : 40 | 6 | 56 |
50 : 50 | 12 | — | |
2b | 60 : 40 | 6 | 78 |
50 : 50 | 12 | 75 | |
40 : 60 | 24 | 61 | |
30 : 70 | 36 | 52 | |
20 : 80 | 48 | — | |
3b | 60 : 40 | 6 | 78 |
50 : 50 | 12 | 70 | |
40 : 60 | 24 | 51 | |
30 : 70 | 36 | — | |
4b | 60 : 40 | 6 | 91 |
50 : 50 | 12 | 67 | |
40 : 60 | 24 | — | |
5b | 60 : 40 | 6 | 77 |
50 : 50 | 12 | 77 | |
40 : 60 | 24 | 56 | |
30 : 70 | 36 | 50 | |
20 : 80 | 48 | — | |
8b | 60 : 40 | 6 | 86 |
50 : 50 | 12 | 85 | |
40 : 60 | 24 | 79 | |
30 : 70 | 36 | 52 | |
20 : 80 | 48 | — | |
20b | 60 : 40 | 6 | 70 |
50 : 50 | 12 | 65 | |
40 : 60 | 24 | 56 | |
30 : 70 | 36 | — | |
21b | 60 : 40 | 6 | 82 |
50 : 50 | 12 | 80 | |
40 : 60 | 24 | 69 | |
30 : 70 | 36 | — | |
25b | 60 : 40 | 6 | 56 |
50 : 50 | 12 | 38 | |
40 : 60 | 24 | — |
Yield of crude products. —: raw material is not well dissolved and the yield is lower than 30%, so it is regarded as no reaction.