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Comparison of the effect of p.o. treatment with RWJ-270201 and oseltamivir on SaO2 decline in influenza B/Hong Kong/05/72 virus-infected mice. ■, RWJ-270201, 100 mg/kg/day; ●, RWJ-270201, 10 mg/kg/day; ▴, RWJ-270201, 1 mg/kg/day; ▾, oseltamivir, 10 mg/kg/day; ▸, oseltamivir, 1 mg/kg/day; ⧫, ribavirin, 75 mg/kg/day; □, PSS; ○ normal controls. ∗, P < 0.05; ∗∗, P < 0.01; ∗∗∗, P < 0.001 (compared to PSS-treated controls). SD, standard deviation.
