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. 2022 Apr 5;13:809642. doi: 10.3389/fmicb.2022.809642

FIGURE 6.

FIGURE 6

Maternal betaine alters the gut microbiota in early-life high-fat diet offspring at 20 weeks of age. The cecal contents were collected from offspring at 20 weeks of age. (A) Shannon index (left) and Simpson index (right); (B) PCoA plots of gut microbiome; (C) relative abundance of the top 10 species at the genus level; (D) relative abundance of Desulfovibrio; (E) relative abundance of Romboutsia; (F) distinct taxa identified in the three groups using LEfSe analysis. The colors represent the group in which the indicated taxa is more abundant compared to the other group. Ctr.20, 20-week-old offspring of dams fed with the standard control diet; HF.20, 20-week-old offspring of dams fed with the high-fat diet; HFB.20, 20-week-old offspring of dams fed with the high-fat diet with betaine. Data are expressed as means ± S.E.M. (n = 5–6/group). One-way ANOVA; **p < 0.01 vs. Ctr, #p < 0.05 vs. HF.