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. 2021 Jul 28;11(42):26016–26028. doi: 10.1039/d1ra04154a

Mean extraction recoveries and matrix effects of the seven flavonoids and IS in rat plasma (n = 6).

Compounds spiked concentration (ng mL−1) Extraction recovery Matrix effect
Mean (%) RSD (%) Mean (%) RSD (%)
Linarin
6.85 89.02 3.16 80.67 3.67
723.73 85.42 5.94 85.34 7.97
2861.18 87.57 2.95 91.27 4.45
Rutin
6.05 87.68 2.86 101.5 3.65
102.57 88.75 5.64 95.10 4.18
418.53 86.76 3.53 90.13 5.29
Luteolin
6.32 83.43 4.42 83.56 3.13
62.17 96.21 6.57 85.86 6.71
247.58 88.84 7.32 87.47 7.16
Quercetin
2.64 87.39 2.64 96.49 5.48
16.38 88.64 4.89 88.77 4.23
64.48 90.05 7.13 97.64 6.26
Apigenin
7.08 89.77 2.39 101.2 5.87
116.93 87.16 3.42 93.28 2.16
468.54 96.89 4.08 90.09 1.93
Acacetin
4.62 85.48 4.42 84.07 2,67
26.17 89.66 7.21 87.59 5.26
102.14 84.06 2.95 91.28 4.98
Acteoside
2.03 89.10 3.95 87.31 5.18
519.32 90.69 4.78 84.23 7.34
2027.29 85.25 5.23 90.79 5.87
Sulfamethoxazole (IS)
476 98.41 3.78 95.67 3.28