Inhibitory activities of 5a–h against human SIRT1.
| Compound | % inhibition of SIRT1 | |
|---|---|---|
| 5 μm | 50 μm | |
| 5a | 13 ± 3 | 42 ± 3 |
| 5b | 18 ± 3 | 45 ± 3 |
| 5c | 12 ± 1 | 38 ± 3 |
| 5d | 11 ± 2 | 48 ± 3 |
| 5e | 20 ± 5 | 44 ± 2 |
| 5f | 14 ± 4 | 39 ± 3 |
| 5g | 9 ± 2 | 35 ± 1 |
| 5h | 16 ± 5 | 44 ± 3 |
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.