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. 2021 Jul 29;11(42):26083–26092. doi: 10.1039/d1ra05297g

Recovery and reuse of catalyst 11.

Entry Time (h) Yield (%) of 15aa,b Recovery of 11 ee (%) in 15a
1 24 87 0.06 gc 94.8
2 24 85 0.06 gd 95.0
3 24 87 0.06 ge 93.2
4 28 88 0.05 gf 93.1
5 28 84 0.05 g 94.0
a

Yields refer to the pure and isolated product.

b

The reaction was performed at room temperature with 1 mmol of 12a, 13a, 14a and 5 mol% of 11.

c

Recovered 11 was used as a catalyst in entry 2.

d

Recovered 11 was used as a catalyst in entry 3.

e

Recovered 11 was used as a catalyst in entry 4.

f

Recovered 11 was used as a catalyst in entry 5.