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. 2021 Jul 27;11(42):25867–25879. doi: 10.1039/d1ra03578a

Investigation of the optimal conditions for the synthesis of diphenyl ether in the presence of Cu–ninhydrin@GO–Ni MNPs.

Entry Amount of catalyst (mg) Solvent Base Temperature (°C) Time (min) Yield (%)
1 DMSO KOH 130 300 N.R.
2 30 DMSO KOH 130 120 98
3 20 DMSO KOH 130 160 90
4 35 DMSO KOH 130 105 93
5 30 PEG KOH 130 120 48
6 30 DMF KOH 130 120 72
7 30 H2O KOH Reflux 120 35
8 30 DMSO Na2CO3 130 120 20
9 30 DMSO NaHCO3 130 120 27
10 30 DMSO Et3N 130 120 55
11 30 DMSO NaOCH3 130 120 31
12 30 DMSO NaOH 130 120 74
13 30 DMSO KOH 100 120 67