Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Apr 18;11(1):1115–1125. doi: 10.1080/22221751.2022.2059400

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 3. — SARS-CoV-2 in the pancreas of COVID-19 patients. (A-B) SARS-CoV-2 receptors ACE2 and CD147 were diffusely expressed in the pancreas. In the non-COVID-19 control patient, ACE2 expression was higher in the exocrine gland, and CD147 was evenly expressed. In patients with COVID-19, ACE2 and CD147 expression was much higher in the endocrine gland. (C) SARS-CoV-2 spike antibody staining showed diffuse positive signals (brown) in the sample from the patient with COVID-19 but not in the non-COVID-19 control. (D) The SARS-CoV-2 nucleic acid probe showed positive staining (red particles) in the cytoplasm of pancreatic cells of a patient with COVID-19 but not in that of the non-COVID-19 control.