Table 2.
Moderate group (n = 23) | Severe group (n = 19) | P value | Reference range | |
---|---|---|---|---|
Age (years) | 52.78 ± 15.37 | 65.79 ± 14.73 | 0.008 | |
BMI (kg/m2) | 23.22 ± 3.84 | 21.70 ± 2.67 | 0.202 | |
Glucose (mmol/L) | ||||
0 min | 4.95 ± 0.50 | 5.39 ± 1.02 | 0.238 | 3.9-6.1 |
30 min | 8.80 ± 2.09 | 9.40 ± 2.09 | 0.433 | 6.1-9.4 |
60 min | 9.09 ± 2.22 | 9.92 ± 2.92 | 0.463 | 6.7-9.4 |
120 min | 7.63 ± 1.96 | 8.97 ± 4.38 | 0.595 | 3.9-7.8 |
180 min | 5.68 ± 1.70 | 7.82 ± 5.41 | 0.390 | 3.9-6.1 |
C-peptide (ng/ml) | ||||
0 min | 1.97 ± 0.95 | 2.37 ± 1.01 | 0.060 | 0.30-0.61 |
30 min | 7.76 ± 4.52 | 6.45 ± 3.07 | 0.536 | 1.5-6.1 |
60 min | 8.65 ± 3.34 | 9.30 ± 5.69 | 0.791 | 1.5-6.1 |
120 min | 9.71 ± 3.77 | 9.75 ± 6.38 | 0.640 | |
180 min | 7.72 ± 3.83 | 7.32 ± 4.71 | 0.471 | 0.30-0.61 |
HbA1c (%) | 5.15 ± 0.37 | 6.12 ± 1.60 | 0.001 | 4∼6% |
Glu_AUC | 1375.24 ± 272.38 | 1582.18 ± 588.38 | 0.587 | |
Cp_AUC | 1543.73 ± 547.45 | 1451.97 ± 822.95 | 0.411 | |
CPI | 1.32 E-4 ± 6.98 E-5 | 1.51 E-4 ± 7.09 E-5 | 0.153 | |
20/(FCp*FBG) | 7.45 ± 2.94 | 6.19 ± 4.07 | 0.063 | |
Cpmax/FCp | 6.14 ± 1.79 | 4.78 ± 1.63 | 0.014 |
Abbreviations: HbA1c, hemoglobin A1c; Glu_AUC, area under the curve of glucose in the OGTT; Cp_AUC, area under the curve of C-peptide in the OGTT; Cp, C-peptide; CPI, C-peptide index; FCp, fasting C-peptide; FBG, fasting blood glucose; Cpmax, the maximum value of C-peptide during the OGTT.