Skip to main content
. 2022 Mar 21;154(9):e202112994. doi: 10.1085/jgp.202112994

Table 3.

Volumes of muscle components and concentration conversion factors for human muscle

Component Relative volume (% fiber volume) Comments
SR 3.8 Eisenberg (1983)
Mitochondria 5 Eisenberg (1983)
t-system 0.28 Eisenberg (1983)
JS 0.014 Estimated to be 5% of t-system volume (see text)
Myoplasmic water 69 Fraction of water in whole tissue that is inside fibers, excluding volumes occupied by SR, t-system, and JS
Concentration conversion factors
Whole muscle (kg−1) → fiber (liter−1) 1.18
Whole muscle (kg−1) → myoplasmic water (liter−1) 1.45
Fiber (liter−1) → myoplasmic water (liter−1) 1.23

Other values required for calculations: whole muscle density, 1.05 kg liter−1 (Segal et al., 1986) and protein density, 1.37 kg liter−1 (Fischer et al., 2004; these values give ratio of wet mass/dry mass of whole muscle = 5); extracellular water, 12.5% of total muscle water (Sjogaard et al., 1985).