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. 2021 Sep 1;18(4):921–934. doi: 10.1080/15548627.2021.1964224

Figure 4.

Figure 4.

LC3A-mediated autophagy is engaged in lung cancer cell plasticity. (A) RT-qPCR of LC3A expression in CL1-0 cells transduced with the lentiviral vector encoding shLC3A or scrambled control (SC) for 14 days. ***p < 0.001. (B) Immunoblotting analysis to assess LC3A, SQSTM1, and GAPDH expression in CL1-0 cells transduced with the lentiviral vector encoding shLC3A or scrambled control (SC) for 3 days. (C) Clonogenic assay of CL1-0 cells transduced with the lentiviral vector encoding shLC3A or scrambled control (SC) for 14 days. ***p < 0.001. (D) Cell-tracking migration (left) and matrigel invasion (right) assays of CL1-0 cells transduced with the lentiviral vector encoding shLC3A or scrambled control (SC) for 14 days. ***p < 0.001.