Figure 9.

miR-383 influences inflammation in H₂O₂-treated cardiomyocytes. Cardiomyocytes were transfected with miR-378/miR-383 or NC mimic or co-transfected with a miR-378/miR-383 inhibitor and lentiviral-si-circ_0007059/siNC for 1 d and subsequently exposed to H₂O₂ (0.1 mM) for 1 d. (a) WB quantification of the inflammatory cytokine expression in cardiomyocytes. (B, C, D) ELISA quantification of inflammatory cytokines released into the cardiomyocyte culture medium. **P < 0.01 and ***P < 0.001 versus the CG; ^#P < 0.05 and ^##P < 0.01 versus the H₂O₂ group; ^$P < 0.05 and ^$$ P < 0.01 versus the H₂O₂ + si-circ_0007059 group.