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Comparative histopathology of the lung after challenge with L7 or L2 LASV strains. HE: hematoxylin-eosin coloration. Yellow arrowheads show severe (L7.1 and L2.1) or mild (L2.2) septal thickening. LASV: immunostaining of LASV glycoprotein-2c. Black arrowheads show infected cells. S100A9: immunostaining of neutrophils. GrB: immunostaining of cytotoxic cells. Scale bar: 100 µm.
