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. 2022 Apr 18;23(1):328–335. doi: 10.1080/15384047.2022.2058862

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© 2022 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Curcumin induces the expression of AIM2, IFI16, and NLRC4 inflammasomes in leukemia cells U937.

(a) Cene expression chip analyzed the expression of NLRP1, NLRP3, NLRC4, AIM2, IFI16, ASC, and GSDMD in U937 treated with curcumin (10 μmol/L) for 24 h; (b) validation of NLRC4, AIM2, and IFI16 expression in U937 when treated with curcumin for 24 h by RT-PCR. Each value represents the mean ± SD (*P < .05, **P < .01, ***P < .001); (c) western blot array analyzed protein level of NLRC4, AIM2, and IFI16 h in U937 after treated with curcumin for 24 h.