Study |
Preparative regimen |
Mobilization tech. |
De Souza |
BEAM (300 mg/m² CARM, 800 mg/m² ETO, 800 mg/m² CYTA, 140 mg/m² MEL) |
not clarified |
Martelli 2003 |
BEAC (300 mg/m² CARM, 800 mg/m² ETO, 800 mg/m² CYTA, 140 mg/kg CY) |
G‐CSF 24h after MACOP‐B week 8 OR G‐CSF alone 2 weeks after MACOP‐B |
Gianni |
30 pts: TBI (12.5 Gy total) + 120‐140 mg/m² MEL, then (due to tox.) 18 pts: MITOX 60 mg/m² + MEL 180 mg/m² |
Phase II: HD‐CY (7 g/m²) + G‐CSF or GM‐CSF |
Gisselbrecht |
BEAM (300 mg/m² CARM, 800 mg/m² ETO, 800 mg/m² CYTA, 140 mg/m² MEL) |
after 1st or 2nd ECVBP cycle + G‐CSF |
Haioun |
CBV (6000 mg/m² CY, 300 mg/m² CARM, 1000 mg/m² ETO) |
after 1st or 2nd HD‐MTX course (G‐CSF not mentioned) |
Intragumtonchai |
TBI (12 Gy total) OR 450 mg/m² CARM, 60 mg/kg ETO, 120 mg/kg CY |
7 days after last ESHAP: G‐CSF |
Kaiser |
BEAM (300 mg/m² CARM, 800 mg/m² ETO, 800 mg/m² CYTA, 140 mg/m² MEL) |
after 2. or 3. CHOEP with G‐CSF |
Kluin‐Nelemans |
BEAC (300 mg/m² CARM, 800 mg/m² ETO, 800 mg/m² CYTA, 140 mg/kg CY) |
between 4th and 6th CHVmP/BV cycle + G‐CSF or GM‐CSF |
Martelli 1996 |
BEAC (300 mg/m² CARM, 800 mg/m² ETO, 800 mg/m² CYTA, 140 mg/kg CY) |
bone marrow collection at a median of 10 days after response evaluation |
Milpied |
BEAM (300 mg/m² CARM, 1600 mg/m² ETO, 1600 mg/m² CYTA, 140 mg/m² MEL) |
after 1st or 2nd CEEP |
Rodriguez 2003 |
BEAM |
stem cell collection after 3x ATT and 2 intensified dose chemotherapy |
Santini 1998 |
BEAM (according to Mills) |
bone marrow collection after last VACOP‐B cycle |
Santini 2003 |
BEAM |
peripheral blood progenitor cells were collected after HD‐CY plus G‐CSF |
Verdonck |
120 mg/kg CY + TBI (8 Gy total [1 fraction only]) |
bone marrow collection after 3x CHOP |
Vitolo |
60 mg/m² MITOX + 180 mg/m² MEL |
not clarified |