| Study |
% HD and SCT |
Reasons for not |
| De Souza |
18/28 (64%) |
3x refusal, 7x death |
| Martelli 2003 |
45/75 (60%) |
7x refusal, 2x inadequate collection , 12x early progression, 1x death, 3x low performance status, 1x thrombosis/embolic event, 1x BM involvement, 1x ulcer perforation, 1x hyperglycaemic coma, 1x acute occlusion femoral artery |
| Gianni |
48/48 (100%) |
all patients received HDT |
| Gisselbrecht |
139/189 (74%) |
24x progression, 3x refusal, 9x severe toxicity during induction, 8x death, 6x miscellaneous |
| Haioun |
198/268 (74%) |
"most commonly refusal or early relapse" |
| Intragumtornchai |
14/23 (61%) |
5x death, 2x refusal, 2x "protocol violation" |
| Kaiser |
103/158 (65%) |
19x lack of response/progression, 14x refusal, 4x concomitant disease, 5x toxicity of induction, 2x collection failure, 7x others, 3x death |
| Kluin‐Nelemans |
60/98 (61%) |
12x relapse/progression, 6x toxicity, 15x refusal, 5x lost to FU/no data |
| Martelli 1996 |
22/29 (76%) |
3x progression, 1x refusal, 2x medical decision, 1x protocol violation |
| Milpied |
83/98 (85%) |
13x: progression or no PR and CR |
| Rodriguez 2003 |
44/59 (75%) |
not reported |
| Santini 1998 |
45/63 (71%) |
1x ineligible, 2x death, 5x refusal, 10x progression |
| Santini 2003 |
79/117 (68%) |
10x refusal, 7x toxicity, 14x progressive disease or death, 5x ineligible, 1x lost to follow‐up, 1x protocol violation |
| Verdonck |
26/34 (76%) |
5x progression, 3x refusal |
| Vitolo |
50/60 (83%) |
‐ |
| Haioun (subgroup) |
86/125 (69%) |
‐ |
