Sub-acute effect of the aqueous extract and nanoparticles of M. zapota leaf extract on the hematological parameters in FCA-induced arthritic ratsa.
| Groups | ESR (mm/1st an Hour) | Hemoglobin content (g dL−1) | RBC's count (106 μL−1) | WBC's count (1000 μL−1) | Platelet count (1000 μL−1) |
|---|---|---|---|---|---|
| Normal control | 2.50 ± 1.00 | 13.68 ± 0.34 | 7.53 ± 0.41 | 7.55 ± 3.15 | 584.3 ± 35.14 |
| Arthritic control | 10.50 ± 2.52*a | 10.28 ± 0.51*a | 4.55 ± 0.70*a | 18.85 ± 1.57*a | 848 ± 49.71*a |
| Positive control | 3.00 ± 1.16* | 13.50 ± 0.26* | 7.28 ± 0.34* | 8.15 ± 0.59* | 555.8 ± 28.66* |
| AEMZ (200 mg kg−1) | 5.00 ± 1.16* | 12.28 ± 0.45* | 6.50 ± 0.45* | 9.73 ± 0.84* | 685.8 ± 120.2* |
| AEMZ (400 mg kg−1) | 4.50 ± 1.00* | 12.43 ± 0.15* | 6.80 ± 0.57* | 9.23 ± 0.54* | 604.5 ± 57.05* |
| NPMZ (5 mg kg−1) | 4.00 ± 1.63* | 12.65 ± 0.26* | 7.08 ± 0.28* | 8.80 ± 0.55* | 652.8 ± 92.69* |
a
Statistical Analysis of the results was conducted between the arthritic group and the control group using the unpaired t-test. Comparison among the arthritic group and all other groups was conducted using one way ANOVA, followed by Dunette's test. Values are expressed in mean ± SD (n = 4). (*ap < 0.05) represents significance.