Table 3.

Analgesic Outcomes by Control Group or Clonidine Group

Variable	Control (n=138)	Clonidine (n=22)	P-value
Analgesic Management and Outcomes
Delivery-to-discharge interval (days)	3 [3, 4]	3 [3, 3]	0.01
Average Oxycodone Equiv per 24hrs (mg)	82.36 [67.78, 109.44]	41.67 [33.33, 48.33]	<0.001
Oxycodone Equiv Day 0 (0–24h)	100 [75, 123.33]	40.84 [25, 50]	<0.001
Oxycodone Equiv Day 1 (24–48h)	85 [65, 120]	50 [40, 50]	<0.001
Oxycodone Equiv Day 2 (48–72h)	75 [50, 102.5]	40 [25, 45]	<0.001
Oxycodone Equiv Day 3 (72–96h)	60 [40, 90]	30 [10, 45]	0.03
First Analgesic Request (spinal dose to first postoperative analgesic medication – minutes)	153.5 [122, 192.5]	207 [168, 323]	<0.001
Average Daily Maximum (highest) Pain Score (0–10)	8.33 [7.67, 9]	7.84 [7, 8.75]	0.18
Pain Day 0 (0–24h)	9 [8, 10]	9 [7, 10]	0.22
Pain Day 1 (24–48h)	8 [7, 9]	8 [7, 9]	0.56
Pain Day 2 (48–72h)	8 [7, 9]	7 [6, 8]	0.09
Pain Day 3 (72–96h)	7 [7, 8]	7 [4.5, 7.5]	0.27
Average Daily Minimum (lowest) Pain Score (0–10)	2.67 [1.67, 3.67]	1.88 [1.33, 3]	0.08
Pain Day 0 (0–24h)	3 [2, 4]	2.5 [0, 3]	0.01
Pain Day 1 (24–48h)	2 [0, 4]	3 [1, 4]	0.53
Pain Day 2 (48–72h)	3 [0, 4]	1 [0, 3]	0.11
Pain Day 3 (72–96h)	3 [0, 4]	0 [0, 4]	0.48
Ketorolac (0–24h) (mg)	120 [90, 120]	120 [120, 120]	0.37
Ibuprofen (mg per 24 hrs)	2933.33 [2666.67, 3200]	3200 [3200, 3200]	0.01
Acetaminophen (mg per 24 hrs)	568.75 [108.33, 1516.67]	1895.84 [433.33, 2383.33]	<0.001
IV PCA use (n (%))	12 (9%)	0 (0%)	0.15
Supplemental Nerve Blocks (n (%))	6 (4%)	1 (5%)	0.97
Hospital Readmission within 30 days (n (%))	6 (4%)	1 (5%)	0.97
Infection (n)	3	1
Preeclampsia (n)	1
Postpartum depression (n)	1
Substance abuse (n)	1

Note: Data shown are n (%) for binary outcomes, and median [25th to 75th percentile range] otherwise.