Table 1. General and disease characteristics of COVID-19 patients.
| Overall (n = 190) | Dead (n = 47) | Alive (n = 143) | P value | |
|---|---|---|---|---|
| Age (years) | 61.5 (49.9–72.1) | 72.6 (62.6–79.6) | 57.7 (48.5–67.2) | <0.0001 |
| Male sex | 122 (64) | 30 (63) | 92 (64) | >0.99 |
| Comorbidities | ||||
| ≥1 comorbidity | 98 (52) | 35 (74) | 63 (44) | 0.00056 |
| Number of comorbidities | 0.9 (0.008) | 1.5 (0.18) | 0.7 (0.082) | <0.0001 |
| HTN | 78 (41) | 27 (57) | 51 (36) | 0.014 |
| COPD | 10 (5) | 6 (13) | 4 (3) | 0.023 |
| CAD | 22 (11) | 12 (25) | 10 (7) | 0.0015 |
| DM | 39 (20) | 15 (32) | 24 (17) | 0.043 |
| CKD | 17 (9) | 9 (19) | 8 (6) | 0.011 |
| Active neoplasia | 6 (3) | 3 (6) | 3 (2) | 0.32 |
| Time from symptom onset to sampling (days) | 8 (4–11) | 5 (2–8) | 8 (5–11) | <0.0001 |
| At hospital admission | ||||
| PaO2/FiO2 | 278.5 (190.5–334.6) | 159.1 (79.2–266.6) | 304.5 (238.1–348.0) | <0.0001 |
| NLR | 5.3 (3.5–8.5) | 9.9 (5.4–13.5) | 4.8 (3.2–7.2) | <0.0001 |
| CRP (mg/dL) | 78.8 (30.3–153.3) | 151.1 (79.4–213.6) | 68.7 (20.4–125.6) | <0.0001 |
| LDH (U/L) | 383 (275–493.5) | 440 (365–627) | 354 (271.5–466.5) | 0.00040 |
| Hospitalization | 152 (80) | 46 (98) | 106 (74) | <0.0001 |
| Length of stay (days)† | 12 (4–22) | 12 (3–24) | 12 (3–24) | 0.44 |
| ICU transfer | 41 (22) | 22 (47) | 19 (13) | <0.0001 |
| Death | 47 (25) | 47 (100) | 0 | - |
| Therapy during hospitalization | ||||
| Steroids | 43 (23) | 22 (47) | 21 (15) | <0.0001 |
| LMWH | 86 (45) | 25 (53) | 61 (43) | <0.020 |
Categorical variables were expressed as count (percentage), while continuous variables as median (interquartile range), with the exception of the number of comorbidities which was expressed as mean (standard deviation).
† Calculated as the time from hospital admission to death or discharge.
Abbreviations: PaO2/FiO2, ratio of arterial oxygen partial pressure to fractional inspired oxygen; NLR, neutrophil to lymphocyte ratio; ICU, intensive care unit, LMWH, low molecular weight heparin