Table 4. Morphokinetic differences between embryo with and without biopsy.
| Morphokinetic parameters | Biopsy Day 5 or Day 6 | No biopsy | Univariate p value | Multivariate analysis | |||
|---|---|---|---|---|---|---|---|
| mean ± SD | n | mean ± SD | n | p value | OR [95%CI] | ||
| Treatment | 0.51 ± 0.50 | 233 | 0.46 ± 0.50 | 137 | 0.211 | ||
| ct2 | 2.6 ± 1.1 | 233 | 4.2 ± 4.4 | 132 | 0.0001 | 0.045 | 0.840 [0.709–0.996] |
| ct3 | 13.0 ± 2.9 | 233 | 12.0 ± 7.8 | 131 | 0.101 | ƚ | |
| ct4 | 14.6 ± 3.4 | 233 | 15.8 ± 8.6 | 122 | 0.341 | ||
| ct5 | 26.2 ± 6.0 | 233 | 21.7 ± 12.0 | 116 | <0.0001 | ƚ | |
| ct6 | 28.6 ± 6.4 | 233 | 27.4 ± 12.2 | 106 | 0.036 | 0.043 | 0.943 [0.890–0.998] |
| cc2.t3-t2 | 10.3 ± 2.9 | 233 | 7.8 ± 6.1 | 129 | <0.0001 | 0.004 | 1.148 [1.044–1.263] |
| cc3.t5-t3 | 13.3 ± 5.0 | 233 | 10.6 ± 10.2 | 115 | 0.0001 | <0.0001 | 1.177 [1.107–1.251] |
| s2.t4-t3 | 1.7 ± 3.4 | 233 | 4.0 ± 5.2 | 121 | <0.001 | 0.005 | 0.886 [0.814–0.964] |
Early morphokinetic parameters (hours) to detect differences between embryos with and without biopsy.
ƚ: Not Estimated due to collinearity with cc2 and cc3, respectively, SD: standard deviation, n: number, OR: odds ratio, CI: confidence interval.