Table 6. Budget impact analysis for nation-wide scale-up of different scenarios plausible to Laos’ context.

Scenario	Scenario breakdown	Cost (US$)	Total Cost (US$)	DALYs averted	Total DALYs averted	Incremental budget impact*	Incremental effect impact (DALYs averted)**
Reference scenario: "Unsupervised PMQ strategy" in all health facilities	-	394,392		446.30		Reference	Reference
Alternative scenario 1: "G6PD test with unsupervised PMQ strategy" in all hospitals and health centers with more than or equal 5 PV cases in a year and "Unsupervised PMQ strategy" in health centers with less than 5 PV cases in a year	"G6PD test with unsupervised PMQ strategy" in all hospitals and health centers with more than or equal 5 PV cases in a year	165,644	476,493	902.3	919.57	82,101	473.27
	"Unsupervised PMQ strategy" in health centers with less than 5 PV cases in a year	310,849		17.27
Alternative scenario 2: "G6PD test with unsupervised PMQ strategy" in all hospitals and health centers regardless of PV case load	-	840,139		938.62		445,747	492.32
Alternative scenario 3: "G6PD test with supervised PMQ strategy" in all hospitals and health centers with more than or equal 5 PV cases in a year and "Unsupervised PMQ strategy" in health centers with less than 5 PV cases in a year	"G6PD test with supervised PMQ strategy" in all hospitals and health centers with more than or equal 5 PV cases in a year	287,408	598,257	1,128.89	1,146.16	203,865	699.86
	"Unsupervised PMQ strategy" in health centers with less than 5 PV cases in a year	310,849		17.27

* Incremental budget impact was calculated by deducting the total cost of the reference scenario from the total cost of an alternative scenario.

** Incremental effect impact was calculated by deducting the total DALYs averted of the reference scenario from the total DALYs averted of an alternative scenario.