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. 2021 Aug 20;11(45):28223–28270. doi: 10.1039/d1ra04181a

Scheme 32. Chemo-enzymatic synthesis of ent-3-epi-casuarine (259), ent-casuarine (260), 2-epi-casuarine (262) and 2,3-di-epi-casuarine (263) via stereodivergent aldol reactions using d-fructose-6-phosphate aldolase (FSA), l-rhamnulose-1-phosphate aldolase (RhuA), and l-fuculose-1-phosphate aldolase (FucA).

Scheme 32