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. Author manuscript; available in PMC: 2022 May 1.
Published in final edited form as: Nature. 2021 Sep 21;599(7885):465–470. doi: 10.1038/s41586-021-04017-w

Extended Data Fig. 8: Mouse and human C1q binding of Fc domain variants of IgG1.

Extended Data Fig. 8:

The capacity of IgG1 Fc domain variants to interact with mouse (a) and human (b) C1q was assessed by ELISA (n= 1 experiment performed in duplicates). The KA (K322A) variant, which has previously described as a complement-deficient mutant28, was included as control.