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. 2022 Apr 25;11:e70810. doi: 10.7554/eLife.70810

Table 3. Hub cell fate conversion after EGFR pathway activation.

Gal4 driver UAS lines (BDSC #) Days at 29 °C % Testes with GFP-marked cells outside the hub
E132-Gal4, Gal80ts UAS-G-TRACE (28280) 8 0% (n = 0/39)
UAS-G-TRACE (28280); UAS-Egfr Type II (9533) 61% (n = 19/31)****
UAS-G-TRACE (28280); UAS-Pointed.P1 (869) 38% (n = 19/50)****
UAS-G-TRACE (28280); UAS-Pointed.P2 (399) 22% (n = 4/18)**
UAS-G-TRACE (28280); UAS-Sprouty-RNAi (36709) 36% (n = 32/89)****
UAS-G-TRACE (28280); UAS- Pten-RNAi (33643) 18% (n = 6/34)**
E132-Gal4, Gal80ts UAS-G-TRACE (28281) 8 0% (n = 0/84)
UAS-Egfr Type I (9534); UAS-G-TRACE (28281) 2% (n = 1/47)ns

Percentages in bold are significant compared to the negative control (corresponding UAS-G-TRACE alone).

Fisher’s Exact Test: **p < 0.01, ****p < 0.0001, ns = not significant.