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. 2022 Apr 25;11:e70810. doi: 10.7554/eLife.70810

Table 4. Overexpression of EGF ligands in the adult testis niche does not cause hub cell proliferation.

Gal4 driver UAS line Source Days at 31 °C % Testes with PH3-positive hub cells
C587-Gal4, Gal80ts UAS-GFP-RNAi BDSC 9330 or 9331 7 0% (n = 0/294)*
UAS-secreted spitz BDSC 63134 7–9 0% (n = 0/219)a,ns
UAS-secreted spitz BDSC 58436 7 0% (n = 0/75)a,ns
UAS-gurken ΔTC Queenan et al., 1999 7 0% (n = 0/82)a,ns
UAS-secreted gurken BDSC 58417 7 0% (n = 0/118)a,ns
UAS-secreted keren Urban et al., 2002 7 0% (n = 0/113)a,ns
UAS-vein Schnepp et al., 1996 6 0% (n = 0/96)a,ns
E132-Gal4, Gal80ts UAS-GFP-RNAi BDSC 9330 or 9331 7 0% (n = 0/237)*
UAS-secreted spitz BDSC 63134 7 0% (n = 0/208)a,ns
UAS-secreted spitz BDSC 58436 7 0% (n = 0/92)a,ns
UAS-gurken ΔTC Queenan et al., 1999 7 0% (n = 0/86)a,ns
UAS-secreted gurken BDSC 58417 7 1% (n = 1/77)a,ns
UAS-secreted keren Urban et al., 2002 7 0% (n = 0/113)a,ns
UAS-vein Schnepp et al., 1996 --- ---
C587-Gal4, Gal80ts UAS-secreted spitz +UAS-Argos-RNAi BDSC 63134 +BDSC 28383 7–9 2% (n = 4/203)b,ns

Fisher’s Exact Test: ns = not significant (a, compared to UAS-GFP-RNAi control; b, compared to UAS-Argos-RNAi BDSC 28383 alone [Table 1]).

*

Data from Table 1.