Table 2. Change in cell abundance due to age, sex, and COVID-19 severity fold difference (log₂) [± 95% CI].

	CD4+ T*	ILC*	CD8+ T*	CD16+ NK*
Age	–0.012***	–0.043***	–0.009*	0.021***
	[–0.018,–0.005]	[–0.053,–0.033]	[–0.016,–0.002]	[0.010, 0.032]
Male	–0.409***	–0.334*	–0.177	0.184
	[–0.618,–0.201]	[–0.659,–0.010]	[–0.406, 0.051]	[–0.169, 0.538]
Hospitalized	0.168	–0.835***	0.227	–1.205***
	[–0.084, 0.421]	[–1.228,–0.441]	[–0.050, 0.503]	[–1.633,–0.778]
Outpatient	0.332*	–0.088	–0.023	–0.522*
	[0.082, 0.581]	[–0.478, 0.302]	[–0.298, 0.253]	[–0.948,–0.095]
R2	0.275	0.478	0.070	0.232

*p< 0.05, **p < 0.01, ***p < 0.001.

^*per 10⁶ lymphocytes.