FIGURE 1.

The COVID-19–associated age-adjusted case fatality rates among kidney transplant recipients and the general population in the state of São Paulo, Brazil. A, Comparison of COVID-19–associated case fatality rates, stratified by age, between kidney transplant recipients and the general population of the state of São Paulo, Brazil, before the COVID-19 immunization. Among 1375 kidney transplant recipients diagnosed with COVID-19 between March 2020 and March 2021, 342 died, reaching a case fatality rate of 24.9%. In the same period; 2.63 million people were diagnosed with COVID-19 in the state of São Paulo; and 91 806 died, yielding a case fatality rate of 3.5%. The data of the general population were extracted from the public and anonymized official registry provided by the government of the State of São Paulo.⁵ B, Comparison of COVID-19–associated case fatality rates, stratified by age, before and after the immunization of kidney transplant recipients. Between March 2020 and March 2021, before vaccination, there were 342 deaths among 1375 kidney transplant recipients diagnosed with COVID-19, reaching an overall case fatality rate of 24.9%. The immunization of the kidney transplant recipients at the transplant center started on March 20, 2021, as part of the prospective phase IV study with CoronaVac. Between May 10, 2021, 28 d after the second dose of vaccine, and January 4, 2022, there were 181 deaths among 664 patients diagnosed with COVID-19, yielding a case fatality rate of 27.3%. COVID-19, coronavirus disease 2019.