Table 2.
Body weight and serum biochemical profiles of ApoE−/− mice.
| Parameters | SLD (n = 6) | HFD (n = 6) | HUA+HFD (n = 6) |
|---|---|---|---|
| Body weight (g) | 27.22 ± 1.03 | 29.17 ± 1.52∗ | 27.0 ± 0.95+ |
| sUA (μmol/l) | 247.3 ± 35.43 | 490.20 ± 106.00∗∗ | 1066.00 ± 180.90+++ |
| TG (mmol/l) | 1.20 ± 0.51 | 3.22 ± 0.19∗∗∗ | 3.39 ± 0.52 |
| TC (mmol/l) | 5.79 ± 1.41 | 43.09 ± 1.08∗∗∗ | 43.21 ± 2.21 |
| HDL-C (mmol/l) | 3.36 ± 0.42 | 2.74 ± 0.82 | 5.05 ± 1.13+ |
| LDL-C (mmol/l) | 1.11 ± 0.41 | 18.13 ± 1.67∗∗∗ | 13.94 ± 1.64+ |
Data are means ± SD. HDL-C: high-density lipoprotein-cholesterol; HFD: high fat diet; HUA+HFD: high level of uric acid and high fat diet; LDL-C: low-density lipoprotein-cholesterol; SLD: standard laboratory diet; sUA: serum uric acid; TC: total cholesterol; TG: triglycerides. ∗P < 0.05, ∗∗P < 0.01, and ∗∗∗P < 0.001 compared to SLD; +P < 0.05 and +++P <0.001 compared to HFD.