Figure 2.

Clustering of cytokine profiles (IL-6, IL-10, CXCL10, TNF-α, S100A4, RANTES, and TGF-β1) in blood plasma of 111 patients with ICUS, CCUS, LR-MDS, and HR-MDS. Age = patients <60 and >60 years old. All cytokine levels are shown after log2-transformation and normalization. CCUS = clonal cytopenias of undetermined significance; CXCL10 = C-X-C motif chemokine 10; HR-MDS = higher-risk myelodysplastic syndromes; ICUS = idiopathic cytopenias of undetermined significance; IL = interleukin; LR-MDS = lower-risk myelodysplastic syndromes; RANTES = regulated on activation normal T-cell expressed and secreted; TNF-α = tumor necrosis factor α.