Table 1.
Estimated parameters describing the changes over time in the proportion of CD8+ T cells specific for each tetramer in different tissues.
| Parameter | Tissue | Tetramer | ||
|---|---|---|---|---|
| AAV | DFE | VAY | ||
| Peak proportion (%) | BAL | 5.23 | 2.52 | 1.80 |
| Lung | 3.37 | 2.10 | 0.90 | |
| NT | 2.53 | 1.12 | 0.83 | |
| TBLN | 1.31 | 0.55 | 1.23 | |
| PBMC | 0.33 | 0.97 | 0.20 | |
| Spleen | 0.55 | 0.50 | 0.38 | |
| Time of peak proportion (days post infection) | BAL | 28.0 | 11.2 | 11.1 |
| Lung | 22.1 | 15.9 | 13.6 | |
| NT | 19.3 | 9.5 | 11.1 | |
| TBLN | 15.1 | 10.3 | 11.9 | |
| PBMC | 16.8 | 3.4 | 9.1 | |
| Spleen | 19.1 | 5.3 | 6.0 | |
| Baseline proportion (%)a | BAL | 0.71 | ||
| Lung | 0.22 | |||
| NT | 0.41 | |||
| TBLN | 0.16 | |||
| PBMC | 0.10 | |||
| Spleen | 0.09 | |||
BAL broncho-alveolar lavage, NT nasal turbinate, TBLN tracheo-bronchial lymph node.
aBaseline proportion is the same for each of the tetramers.