TABLE 4.
PBP (species) | Box 1
|
Spacing | Box 2
|
Spacing | Box 3
|
Spacing | Box 4
|
Spacing | Box 5
|
Spacing | Box 6
|
Spacing | Box 7
|
Spacing | Box 8
|
Spacing | Box 9
|
Spacing |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
EDX(R/K)FXEHXG | GAST(I/L)(T/S)QQ | RKX2E | KXEILEXYXN | R(R/Q)X2VL | GX4TTX5Q | SXXK | SXN | K(T/S)G | ||||||||||
PBP 1 (L. interrogans) | 120 | 20 | 150 | 14 | 172 | 12 | 189 | 55 | 254 | 89 | 349 | 84 | 446 | 50 | 500 | 133 | 636 | 166 |
EDREFYNHHG | GGSTSTQQ | NKITE | KNTILSMYLN | RQKLVL | GMNVYTTLDYDKQ | STIK | SIN | KTG | ||||||||||
PBP 1b (Synechocystis sp.) | 113 | 21 | 144 | 14 | 166 | 12 | 183 | 55 | 248 | 60 | 314 | 63 | 390 | 54 | 448 | 119 | 570 | 79 |
EDSNFYKHQG | GASTLSMQ | RKLAE | KDQILDMYLN | RQEVVL | GLRVQSTVDYDTQ | SAFK | SAN | KTG | ||||||||||
PBP 1 (N. gonorrhoeae) | 88 | 21 | 119 | 14 | 141 | 12 | 158 | 55 | 223 | 57 | 286 | 162 | 461 | 56 | 521 | 127 | 651 | 146 |
EDKRFYRHWG | GASTITQQ | RKFNE | KDKILELYFN | RQKYIL | GFKVYTTVRTDHQ | STFK | SKN | KTG | ||||||||||
PBP 1a (E. coli) | 86 | 21 | 117 | 14 | 139 | 12 | 156 | 55 | 221 | 57 | 284 | 168 | 465 | 55 | 524 | 189 | 716 | 133 |
EDSRFYEHHG | GASTITQQ | RKIKE | KDEILELYLN | RRNVVL | GYRIYTTITRKVQ | SNIK | SKN | KTG |
PBP 1 sequences from L. interrogans strains Verdun and RZ11 have the same conserved boxes. Numbers above the sequences indicate the positions. Spacing indicates the number of amino acids between boxes. Amino acids conserved between PBPs are indicated in boldface; where they are not conserved, they are underlined.