Table 2:

Polyserial Correlations^& of Ped-PRO-CTCAE Symptomatic AEs with PROMIS Pediatric Measures

		PROMIS Pediatric T-score
Pediatric PRO-CTCAE	Attribute	Depression	Anxiety	Fatigue
		r	r	r
Abdominal Pain	Frequency1	0.34	0.31	0.45
	Severity2	0.34	0.35	0.44
	Interference3	0.32	0.31	0.41
Anorexia	Frequency1	0.29	0.31	0.31
Nausea	Frequency1	0.35	0.32	0.42
	Severity2	0.39	0.35	0.45
	Interference3	0.37	0.30	0.45
Vomiting	Frequency1	0.27	0.22	0.31
	Interference3	0.36	0.31	0.37
Constipation	Frerquency1	0.13	0.15	0.26
	Severity2	0.16	0.20	0.32
	Interference3	0.31	0.21	0.29
Diarrhea	Frequency1	0.17	0.16	0.19
	Interference3	0.31	0.19	0.30
Cough	Frequency1	0.14	0.11	0.11
	Severity2	0.16	0.13	0.17
	Interference3	0.32	0.28	0.34
Pain	Frequency1	0.33	0.36	0.49
	Severity2	0.30	0.33	0.47
	Interference3	0.34	0.31	0.52
Headache	Frequency1	0.34	0.31	0.39
	Severity2	0.38	0.34	0.41
	Interference3	0.42	0.36	0.41
Neuropathy	Severity2	0.35	0.38	0.36
	Interference3	0.46	0.44	0.48
Mucositis	Frequency1	0.20	0.26	0.24
	Severity2	0.24	0.27	0.27
	Interference3	0.26	0.31	0.28
Anxiety	Frequency1	0.69	0.77	0.48
	Severity2	0.64	0.73	0.44
	Interference3	0.68	0.64	0.56
Depression	Severity2	0.74	0.63	0.47
	Interference3	0.71	0.63	0.50
Fatigue	Severity2	0.46	0.43	0.58
	Interference3	0.44	0.41	0.60
Insomnia	Frequency1	0.39	0.39	0.39
	Severity2	0.39	0.41	0.42
	Interference3	0.46	0.38	0.49

¹: 0=Never, 1=Sometimes, 2=Most of the time, 3=Almost all the time.

²: 0=Did not have any, 1=A little bad, 2=Bad, 3=Very bad.

³: 0=Not at all, 1=Some, 2=A lot, 3=A whole lot.

Note

r>0.50 large positive correlation, r >0.3–0.4= moderate positive correlation