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. Author manuscript; available in PMC: 2023 Jun 1.
Published in final edited form as: J Surg Res. 2022 Feb 5;274:94–101. doi: 10.1016/j.jss.2021.12.037

Figure 5: Neutrophils from septic mice have impair phagocytosis.

Figure 5:

Mice underwent sham treatment (n=32), surgical CLP injury (n=25) or CLP injury with subsequent surgical source control (CLP/E) after 3h (n=20). After 24h post injury, whole blood was harvested and the cells were incubated with particles labelled with pH-sensitive dyes, as described in the method section. The acidification of the internal cell compartments was analyzed via flow cytometry. Increased acidification correlates with an increased median fluorescent intensity (MFI) of the ingested pH-sensitive particles. Data are presented as a box plot covering the first, second (median), third quartile, and 5th + 95th percentile. # p<0.05 vs sham and CLP/E.