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. Author manuscript; available in PMC: 2023 May 15.
Published in final edited form as: Mol Cell Endocrinol. 2022 Mar 15;548:111617. doi: 10.1016/j.mce.2022.111617

Figure 3.

Figure 3.

FGF19 regulation of glucose homeostasis in the liver, brain, and adipose tissue. fibroblast growth factor (FGF), fibroblast growth factor receptor (FGFR), β-Klotho (KLB), FGFR substrate 2 alpha (FRS2α), extracellular signal-regulated kinase 1/2 (ERK1/2), 90-kDa ribosomal s6 kinase 1 (p90RSK), glycogen synthase kinase (GSK), glucose-6-phophatase (G6pase), phosphoenoylpyruvate kinase (Pepck), cAMP regulatory element-binding protein (CREB), peroxisome proliferator-activated receptor gamma coactivator (PGC-1α), agouti-related peptide (AgRP), neuropeptide Y (NPY), adrenocorticotropic hormone (ACTH), erythroblast transformation specific transcription factor (ELK1), serum response factor (SRF), glucose transporter (GLUT), non-esterified fatty acid (NEFA). Dashed lines represent potential pathways not fully confirmed experimentally.