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. Author manuscript; available in PMC: 2023 May 15.
Published in final edited form as: Mol Cell Endocrinol. 2022 Mar 15;548:111617. doi: 10.1016/j.mce.2022.111617

Figure 5.

Figure 5.

FGF19 signaling in protein synthesis in the liver and skeletal muscle. fibroblast growth factor (FGF), fibroblast growth factor receptor (FGFR), β-Klotho (KLB), FGFR substrate 2 alpha (FRS2α), extracellular signal-regulated kinase 1/2 (ERK1/2), mammalian target of rapamycin (mTOR), regulatory-associated protein of mTOR (Raptor), 90-kDa ribosomal s6 kinase 1 (p90RSK), ribosomal protein S6 kinase beta-1 (p70S6K1), glperoxisome proliferator-activated receptor gamma coactivator (PGC-1α), MAPK interacting protein kinases 1 (Mnk1), eukaryotic initiation factor (eIF), ribosomal protein S6 (S6), sirtuin (SIRT), major histocompatibility complex (MHC), myoblast determination (MyoD), myogenin (MyoG), forkhead/winged helix box gene, group (FOXO), E3 ubiquitin-protein ligase (MuRF). Dashed lines represent potential pathways not fully confirmed experimentally.